AISIntervention

Mechanical thrombectomy
  • Do not delay TPA if indicated.
  • Occlusion of internal carotid artery or M1 segment
  • Age 18 or over
  • Acute stroke onset < 6 hours
    • Prestroke mRS score <2
      • (meaning no significant disability despite symptoms, able to carry out all usual duties and activities before stroke)
    • NIHSS >= 6
  • Acute stroke onset 6-24 hours
  • Only for ICA/MCA occlusion, needs CTP to screen for salvageable penumbra using one of the following criterias:
    • DAWN Criteria: (used clinical imaging mismatch in patients presenting 6-24h)
      • Pre-stroke mRS < 2
      • Anticipated life expectancy > 6 months
      • NIHSS >= 10
      • < 1/3 MCA core infarction
      • Clinical imaging mismatch:
        • < 80-year: Core < 30 with NIHSS >= 10 or Core 30-50 with NIHSS >= 20
        • > 80-year: Core < 20 with NIHSS >= 10
      • Excluded: cervical ICA occlusion, PCA/ACA occlusion, dissection, tortious vessels.
    • DEFUSE 3 Criteria: (used perfusion-core mismatch in patients presenting 6-16h)
      • Age < 90
      • Imaging mismatch: If Core < 70 ml and mismatch ratio > 1.8 with at least 15 ml of viable penumbra.
      • No pre-existing terminal or debilitating illness


Animation of mechanical thrombectomy