Category: Movement

Essential tremor (ET) is the most common cause of tremor. Symptoms and signs persistent bilateral postural tremor > 5 years Action tremor: bilateral, may be asymmetrical postural, kinetic, intention May have head tremor No other abnormal neuro sign except Froment’s sign: cogwheel without rigidity Exacerbated by anxiety, excitement or...

Reduce delusions in Parkinson disease patient 34 mg qd Approved in 2016 not approved for the treatment of patients with dementia-related psychosis Strong cyp3a4 inhibitors Cost 34 mg 30 cap – $3400...

Medication induced usually symmetrical take pt off the offending medication can be caused by older neuroleptic and Metoclopropamide (Reglan) May use anticholinergic for treatment Idiopathic: one side is worse than other. For young onset (<65 years old). start with dopamine agonist, such as ropinirole Older patient, use L dopa...

Entacapone 200 mg with every L dopa dose reduce off time by 1 hour increased on time beneficial effect is independent of age Generic available 200 mg tid, 90 cost $50 Main potential side effect: nausea, dyskinesia...